Epidemiological analysis of corneal donors and patients queuing for keratoplasty
DOI:
https://doi.org/10.53660/CONJ-2027-MP23BPalavras-chave:
Corneal transplantation, Cornea, Free tissue flaps, Tissue donors, BlindnessResumo
Purpose: To characterize corneal donors and patients on the waiting list for keratoplasty clinically and epidemiologically. Methods: Epidemiological, cross-sectional study with a sample of 1,303 donors and 938 patients on the waiting list were analyzed. Performed in MS State Transplant Center (STC) and the Human Ocular Tissue Bank, from January to June 2019. For the qualitative variables, descriptive analysis was performed. In the quantitative variables, trend and data dispersion measures were analyzed. Results: Of the 2,606 corneas, 31.73% were transplanted, 21.64% of donors were reagents for infectious diseases that contraindicated transplantation, with a higher percentage of reagents in donors aged over 50 years (p <0.001). Keratoconus stood out as the main ocular diagnosis in the frequency distribution. The average age found for patients in the waiting line was 49.05 years. Regarding the average waiting time to perform the transplant, it was 108.46 days for elective transplants and 11.0 days for emergency transplants. Conclusion: More than 40% of the tissues taken from donors were discarded, with emphasis on epithelial defects and reagent serologies. Keratoconus was the main indication of patients queuing for keratoplasty.
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ABTO - BRAZILIAN ASSOCIATION OF ORGAN TRANSPLANTATION. Numerical data on organ donation and transplants performed by state and institution in the period: January/June 2019. Brazilian Transplantation Registry. 2019 Jan-Jun; XXV (2):1-23. Available from: http://www.abto.org.br/abtov03/default.aspx?mn=569&c=1130&s=0&friendly=rbt-2019.
ABTO - BRAZILIAN ASSOCIATION OF ORGAN TRANSPLANTATION. Sizing of transplants in Brazil and in each State (2011-2018). Brazilian Transplantation Registry. 2018 Jan-Jun; XXIV (4):1-34. Available from: http://www.abto.org.br/abtov03/default.aspx?mn=566&c=1118&s=0&friendly=rbt-2018.
ABTO - BRAZILIAN ASSOCIATION OF ORGAN TRANSPLANTATION. Sizing of transplants in Brazil and in each State (2007-2014). Brazilian Transplantation Registry. 2014 Jan-Jun; XX (4):1-85. Available from: http://www.abto.org.br/abtov03/Upload/file/RBT/2014/rbt2014-lib.pdf.
ALMEIDA SOBRINHO, E. F.; NEGRÃO, B. C.; ALMEIDA, H. G. Epidemiological profile of patients waiting for penetrating keratoplasty in state of Pará, Brazil. Rev Bras Oftalmol, v. 70, n. 6, p. 384-90, 2011. DOI 10.1590/S0034-72802011000600009
ALMEIDA, H. G.; SOUZA, A. C. D. Epidemiological profile of patients waiting for penetrating keratoplasty in state of Pernambuco – Brazil. Rev Bras Oftalmol, v.73, n.1, p. 28-32, 2014. DOI 10.5935/0034-7280.20140006
ALTAY, Y. et al. Changing indications and techniques for corneal transplantations at a tertiary referral center in Turkey, from 1995 to 2014. Clin Ophthalmol, v. 10, p. 1007-13, 2016. DOI 10.2147/OPTH.S102315
BARBOSA, A. P. et al. Evaluation of penetrating keratoplasty indications in inner part of the São Paulo state. Rev Bras Oftalmol, v. 71, n. 6, p. 353-7, 2012. DOI 10.1590/S0034-72802012000600002
BASTOS, L. M. et al. Evaluation of the level of knowledge about Aids and syphilis among the elderly from a city in the interior of the state of Ceará, Brazil. Ciênc Saúde Colet, v. 23, n. 8, p. 2495-502, 2018. DOI 10.1590/1413-81232018238.10072016
BENSON, M. D. et al. Analysis of penetrating keratoplasty in Northern Alberta, Canada, from 2000 to 2015. Can J Ophthalmol, v. 53, n. 6, p. 568-73, 2018. DOI 10.1016/j.jcjo.2018.01.024.
BERTASI, R. A. O. et al. Profile of potential organ donors and factors related to donation and non- donation of organs in an Organ Procurement Service. Rev Col Bras Cir, v. 46, n. 3, e20192180, 2019. DOI 10.1590/0100-6991e-201922180
BORGES, T. et al. Evolution of Corneal Transplants at the Porto Hospital Center (PHC): from penetrating keratoplasty to lamellar transplants. Oftalmology, v. 40, n. 4, p. 309-16, 2016. DOI: https://doi.org/10.48560/rspo.7542
BRAZIL. Ministry of Health. Consolidation Ordinance n. 4, september 28, 2017. Brasília, DF, 2017. Available from: http://bvsms.saude.gov.br/bvs/saudelegis/gm/2009/prt2600_21_10_2009.html.
BRAZIL. Ministry of Health. Organ Donation: transplants, waiting list and how to be a donor. Brasília, DF, 2019. Available from: http://www.saude.gov.br/saude-de-a-z/doacao-de-orgaos.
BRAZIL. RDC n. 55, december 11, 2015. Brasília, DF, 2015. Available from: https://www.cevs.rs.gov.br/upload/arquivos/201705/18112318-rdc-55-2015-boas-praticas-em-tecidos-14-12-2015.pdf.
COLL, C. B.; URIBE, L. A. P.; MOLANO-GONZÁLEZ, N. Indications and techniques for corneal transplantation in a private ophthalmology clinic in Colombia. Rev Soc Colomb Oftalmol, v. 52, n. 1, p. 8-15, 2019. https://pesquisa.bvsalud.org/portal/resource/pt/biblio-1026287
CONSELHO FEDERAL DE ENFERMAGEM (COFEN). Resolution COFEN number 292/2004. Nurse's role in the Capture and Transplantation of Organs and Tissues. Available in: <http://site.portalcofen.gov.br/node/4328>.
CRUZ, G. K. P. Corneal transplantation in the state of Rio Grande do Norte: epidemiological and clinical aspects. 2015. 100 p. Dissertation (Masters in Nursing) – Health Sciences Center/UFRN, Natal/Brazil, 2015. p. 25-39.
CRUZ, G. K. P. et al. Clinical and epidemiological aspects of cornea transplant patients of a reference hospital. Rev. Latino-Am. Enfermagem., v. 25, e2897, 2017. DOI 10.1590/1518-8345.1537.2897.
CRUZ, G. K. P. et al. Epidemiological situation of patients on the waiting list for corneal transplantation - sectional study. Biosci J, v. 34, n. 6, p. 1751-57, 2018. DOI https://doi.org/10.14393/BJ-v34n6a2018-36224
FREITAS, R. A. et al. Do Donated Corneas Become Transplanted Corneas? The Causes of Discard in Southern Brazil. Cornea, v. 38, n. 4, p. 419-25, 2019. DOI 10.1097/ico.0000000000001856
GOVERNMENT OF THE STATE OF MATO GROSSO DO SUL. Statistical profile of Mato Grosso do Sul, 2018; 2018 [cited 2019 Dec 10]. Available from: http://www.semagro.ms.gov.br/wp-content/uploads/2018/12/Perfil-Estat%C3%ADstico-de-MS-2018.pdf.
HOPKINSON, C. L. et al. The Influence of Donor and Recipient Gender Incompatibility on Corneal Transplant Rejection and Failure. Am J Transplant, v. 17, n. 1, p. 210-7, 2017. DOI 10.1111/ajt.13926.
IBGE - Brazilian Institute of Geography and Statistics. 2010 Population Census: Characteristics of population and households. Rio de Janeiro: IBGE, 2010. Available from: https://censo2010.ibge.gov.br/resultados.html.
LASS, J. H. et al. Cornea Preservation Time Study: Methods and Potential Impact on the Cornea Donor Pool in the United States. Cornea, v. 34, n. 6, p. 601-8, 2015. DOI 10.1097/ICO.0000000000000417.
LOPES, A. C. N.; PINTO, A. G. T.; SOUZA, B. A. Keratoconus: a review. Rev Med Saude Brasilia, v. 4, n. 2, p. 219-32, 2015. https://portalrevistas.ucb.br/
LOPES, A. N.; CASTILHOS, H. D. F. Corneal specular microscopic endothelial evaluation of donors older than 70 years in an eye bank from Serra Gaúcha. Rev Enferm Atenção Saúde, v. 6, n. 2, p. 12-20, 2017. DOI 10.18554/reas.v6i2.2045
NEVES, R. C.; BOTEON, J. E.; SANTIAGO, A. P. M. S. Indications for penetrating corneal graft at the São Geraldo Hospital of Minas Gerais Federal University. Rev Bras Oftalmol, v. 69, n. 2, p. 84-88, 2010. https://www.scielo.br/pdf/rbof/v69n2/a03v69n2.pdf
NOGUEIRA, E. S.; SILVA, E. G.; SANTOS, W. L. Nursing care in cornea transplantation. Rev Inic Cient e Ext, v. 2, n. 2, p. 89-95, 2019. https://revistasfacesa.senaaires.com.br/index.php/iniciacao-cientifica/article/view/151/106
PEREIRA, P. M. M. et al. Corneal transplant at a reference hospital in Northern Brazil. Eletronic J Collection Health, v. 11, n. 11, e419, 2019. DOI https://doi.org/10.25248/reas.e419.2019
PINEDA, R. World corneal blindness. In: Colby K, Dana R. Foundations of Corneal Diseases: Past, Present and Future. Switzerland: Springer Nature Switzerland AG; 2020; pp. 299-305.
ROCON, P. C.; ALMEIDA, A. V.; PARO, F. M. Epidemiological profile of cornea and organ donors in five hospitals in the State of Espírito Santo, Brazil. Rev Bras Pesq Saúde, v. 17, n. 1, p. 56-64, 2015. https://periodicos.ufes.br/rbps/article/view/12450/8660
SILVA, R. E. et al. Epidemiological profile of west center cornea donors. Rev Bras Oftalmol, v. 75, n. 4, p. 274-8, 2016. DOI 10.5935/0034-7280.20160055
SOUZA, A. L. C.; CERQUEIRA, C. N.; NOGUEIRA, E. C. Nursing contribution to reduce potential rejection of corneal transplants. Acta Paul Enferm, v. 24, n. 2, p. 239-243, 2011. https://doi.org/10.1590/S0103-21002011000200013.
VICTER, T. N. F. et al. Causes of death and discard of donated corneal tissues: Federal District eye bank analysis 2014-2017. Rev Bras Oftalmol, v. 78, n. 4, p. 227-232, 2019. DOI 10.5935/0034-7280.20190133
WORLD HEALTH ORGANIZATION. Priority eye diseases. WHO; 2019 [cited 2019 Dec 13]. Available from: https://www.who.int/blindness/causes/priority/en/index8.html.
ZARE, M. et al. Changing indications and surgical techniques for corneal transplantation between 2004 and 2009 at a tertiary referral center. Middle East Afr J Ophthalmol, v. 19, n. 3, p. 323-9, 2012. DOI 10.4103/0974-9233.97941.
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